Ouzo's heritage traces back to ancient Greek distillation practices, with its modern form emerging in the 19th century. The name received official recognition in 1989 as a protected designation of origin product.
The spirit's development is closely linked to the raisin trade and the establishment of the first modern distilleries in Tyrnavos and Lesvos. These regions became crucial centers of ouzo production, with local families developing distinct recipes passed down through generations.